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Infection and Immunity
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Table of Contents

July 2009; Volume 77,Issue 7

Spotlight

  • Free
    Spotlight
    Articles of Significant Interest Selected from This Issue by the Editors

Minireviews

  • Minireview
    This Is Not Your Mother's Repressor: the Complex Role of Fur in Pathogenesis
    Beth M. Carpenter, Jeannette M. Whitmire, D. Scott Merrell

Molecular Pathogenesis

  • Molecular Pathogenesis
    Identification of a Novel Lipopolysaccharide Core Biosynthesis Gene Cluster in Bordetella pertussis, and Influence of Core Structure and Lipid A Glucosamine Substitution on Endotoxic Activity
    Jeroen Geurtsen, Monika Dzieciatkowska, Liana Steeghs, Hendrik-Jan Hamstra, Johanna Boleij, Kelly Broen, Grietsje Akkerman, Hassan el Hassan, Jianjun Li, James C. Richards, Jan Tommassen, Peter van der Ley
  • Molecular Pathogenesis
    The Posttranslocation Chaperone PrsA2 Contributes to Multiple Facets of Listeria monocytogenes Pathogenesis
    Francis Alonzo, Gary C. Port, Min Cao, Nancy E. Freitag
  • Molecular Pathogenesis
    Subcellular Localization of the Staphylococcus aureus Heme Iron Transport Components IsdA and IsdB
    Gleb Pishchany, Susan E. Dickey, Eric P. Skaar
  • Molecular Pathogenesis
    Monoclonal Antibody 11E10, Which Neutralizes Shiga Toxin Type 2 (Stx2), Recognizes Three Regions on the Stx2 A Subunit, Blocks the Enzymatic Action of the Toxin In Vitro, and Alters the Overall Cellular Distribution of the Toxin
    Michael J. Smith, Angela R. Melton-Celsa, James F. Sinclair, Humberto M. Carvalho, Cory M. Robinson, Alison D. O'Brien
  • Molecular Pathogenesis
    Prolonged Impact of Antibiotics on Intestinal Microbial Ecology and Susceptibility to Enteric Salmonella Infection
    Amy Croswell, Elad Amir, Paul Teggatz, Melissa Barman, Nita H. Salzman
  • Molecular Pathogenesis
    CspA-Mediated Binding of Human Factor H Inhibits Complement Deposition and Confers Serum Resistance in Borrelia burgdorferi
    Melisha R. Kenedy, Santosh R. Vuppala, Corinna Siegel, Peter Kraiczy, Darrin R. Akins
  • Molecular Pathogenesis
    Borrelia burgdorferi RevA Antigen Binds Host Fibronectin
    Catherine A. Brissette, Tomasz Bykowski, Anne E. Cooley, Amy Bowman, Brian Stevenson
  • Molecular Pathogenesis
    Shiga Toxin 2 Is Specifically Released from Bacterial Cells by Two Different Mechanisms
    Takeshi Shimizu, Yuko Ohta, Masatoshi Noda
  • Molecular Pathogenesis
    Role of Teichoic Acid Choline Moieties in the Virulence of Streptococcus pneumoniae
    Florian Gehre, Radek Spisek, Arun S. Kharat, Phillip Matthews, Anjli Kukreja, Robert M. Anthony, Madhav V. Dhodapkar, Waldemar Vollmer, Alexander Tomasz
  • Molecular Pathogenesis
    ace, Which Encodes an Adhesin in Enterococcus faecalis, Is Regulated by Ers and Is Involved in Virulence
    Francois Lebreton, Eliette Riboulet-Bisson, Pascale Serror, Maurizio Sanguinetti, Brunella Posteraro, Riccardo Torelli, Axel Hartke, Yanick Auffray, Jean-Christophe Giard
  • Molecular Pathogenesis
    The Metal Homeostasis Protein, Lsp, of Streptococcus pyogenes Is Necessary for Acquisition of Zinc and Virulence
    Benjamin F. Weston, Audrey Brenot, Michael G. Caparon
  • Molecular Pathogenesis
    The Staphylococcus aureus GGDEF Domain-Containing Protein, GdpS, Influences Protein A Gene Expression in a Cyclic Diguanylic Acid-Independent Manner
    Fei Shang, Ting Xue, Haipeng Sun, Lei Xing, Shuo Zhang, Zhenjun Yang, Lihe Zhang, Baolin Sun
  • Molecular Pathogenesis
    An Immunogenic, Surface-Exposed Domain of Haemophilus ducreyi Outer Membrane Protein HgbA Is Involved in Hemoglobin Binding
    Igor Nepluev, Galyna Afonina, William G. Fusco, Isabelle Leduc, Bonnie Olsen, Brenda Temple, Christopher Elkins
  • Molecular Pathogenesis
    Complementation of the fadA Mutation in Fusobacterium nucleatum Demonstrates that the Surface-Exposed Adhesin Promotes Cellular Invasion and Placental Colonization
    Akihiko Ikegami, Peter Chung, Yiping W. Han
  • Molecular Pathogenesis
    Processing of Pseudomonas aeruginosa Exotoxin A Is Dispensable for Cell Intoxication
    Juliette Morlon-Guyot, Jocelyn Méré, Anne Bonhoure, Bruno Beaumelle
  • Molecular Pathogenesis
    Selective Upregulation of Endothelial E-Selectin in Response to Helicobacter pylori-Induced Gastritis
    Helena Svensson, Malin Hansson, Jan Kilhamn, Steffen Backert, Marianne Quiding-Järbrink

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    Salmonella enterica Serovar Typhimurium Pathogenicity Island 1-Encoded Type III Secretion System Translocases Mediate Intimate Attachment to Nonphagocytic Cells
    María Lara-Tejero, Jorge E. Galán
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions | Spotlight
    Liposomes Recruit IpaC to the Shigella flexneri Type III Secretion Apparatus Needle as a Final Step in Secretion Induction
    Chelsea R. Epler, Nicholas E. Dickenson, Andrew J. Olive, Wendy L. Picking, William D. Picking
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Urothelial Cultures Support Intracellular Bacterial Community Formation by Uropathogenic Escherichia coli
    Ruth E. Berry, David J. Klumpp, Anthony J. Schaeffer
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Pseudomonas aeruginosa Inhibition of Flagellin-Activated NF-κB and Interleukin-8 by Human Airway Epithelial Cells
    Jose Pena, Zhu Fu, Christian Schwarzer, Terry E. Machen
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Overexpression of the Natural Inhibitor of Cysteine Peptidases in Leishmania mexicana Leads to Reduced Virulence and a Th1 Response
    Karen Bryson, Sébastien Besteiro, H. Adrienne McGachy, Graham H. Coombs, Jeremy C. Mottram, James Alexander
  • Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
    Mycobacterium avium subsp. paratuberculosis Fibronectin Attachment Protein Activates Dendritic Cells and Induces a Th1 Polarization
    Jun Sik Lee, Sung Jae Shin, Michael T. Collins, In Duk Jung, Young-Il Jeong, Chang-Min Lee, Yong Kyoo Shin, Daejin Kim, Yeong-Min Park

Bacterial Infections

  • Bacterial Infections
    Matrix Metalloproteinase 9 Plays a Key Role in Lyme Arthritis but Not in Dissemination of Borrelia burgdorferi
    Andrew J. Heilpern, Warren Wertheim, Jia He, George Perides, Roderick T. Bronson, Linden T. Hu
  • Bacterial Infections
    The Arginine Catabolic Mobile Element Is Not Associated with Enhanced Virulence in Experimental Invasive Disease Caused by the Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Genetic Background
    Christopher P. Montgomery, Susan Boyle-Vavra, Robert S. Daum
  • Bacterial Infections
    Genetic Requirements for Klebsiella pneumoniae-Induced Liver Abscess in an Oral Infection Model
    Ya-Chun Tu, Min-Chi Lu, Ming-Ko Chiang, Shu-Ping Huang, Hwei-Ling Peng, Hwan-You Chang, Ming-Shiou Jan, Yi-Chyi Lai
  • Bacterial Infections
    OspC-Independent Infection and Dissemination by Host-Adapted Borrelia burgdorferi
    Kit Tilly, Aaron Bestor, Daniel P. Dulebohn, Patricia A. Rosa
  • Bacterial Infections
    Salmonella enterica Serovar Enteritidis Pathogenicity Island 1 Is Not Essential for but Facilitates Rapid Systemic Spread in Chickens
    Taseen S. Desin, Po-King S. Lam, Birgit Koch, Claudia Mickael, Emil Berberov, Amanda L. S. Wisner, Hugh G. G. Townsend, Andrew A. Potter, Wolfgang Köster
  • Bacterial Infections
    Precolonized Human Commensal Escherichia coli Strains Serve as a Barrier to E. coli O157:H7 Growth in the Streptomycin-Treated Mouse Intestine
    Mary P. Leatham, Swati Banerjee, Steven M. Autieri, Regino Mercado-Lubo, Tyrrell Conway, Paul S. Cohen
  • Bacterial Infections
    Purification of Legiobactin and Importance of This Siderophore in Lung Infection by Legionella pneumophila
    Kimberly A. Allard, Jenny Dao, Prakash Sanjeevaiah, Kessler McCoy-Simandle, Christa H. Chatfield, David S. Crumrine, Domenic Castignetti, Nicholas P. Cianciotto
  • Bacterial Infections
    Transcriptional and Translational Analysis of Biofilm Determinants of Aggregatibacter actinomycetemcomitans in Response to Environmental Perturbation
    Jayaleka J. Amarasinghe, Frank A. Scannapieco, Elaine M. Haase
  • Bacterial Infections
    Nonhematopoietic Cells Control the Outcome of Infection with Listeria monocytogenes in a Nucleotide Oligomerization Domain 1-Dependent Manner
    Ahmed Mosa, Christian Trumstedt, Emma Eriksson, Oliver Soehnlein, Frank Heuts, Katrin Janik, Andreas Klos, Oliver Dittrich-Breiholz, Michael Kracht, Åsa Hidmark, Hans Wigzell, Martin E. Rottenberg
  • Bacterial Infections
    Novel Subtilase Cytotoxin Produced by Shiga-Toxigenic Escherichia coli Induces Apoptosis in Vero Cells via Mitochondrial Membrane Damage
    Gen Matsuura, Naoko Morinaga, Kinnosuke Yahiro, Reiko Komine, Joel Moss, Hideo Yoshida, Masatoshi Noda
  • Bacterial Infections
    Evidence for Capsule Switching between Carried and Disease-Causing Neisseria meningitidis Strains
    Amanda J. Beddek, Ming-Shi Li, J. Simon Kroll, T. William Jordan, Diana R. Martin
  • Bacterial Infections
    Glucose and Glycolysis Are Required for the Successful Infection of Macrophages and Mice by Salmonella enterica Serovar Typhimurium
    Steven D. Bowden, Gary Rowley, Jay C. D. Hinton, Arthur Thompson

Host Response and Inflammation

  • Host Response and Inflammation
    Chlamydial Heat Shock Protein 60 Induces Acute Pulmonary Inflammation in Mice via the Toll-Like Receptor 4- and MyD88-Dependent Pathway
    Yonca Bulut, Kenichi Shimada, Michelle H. Wong, Shuang Chen, Pearl Gray, Randa Alsabeh, Terence M. Doherty, Timothy R. Crother, Moshe Arditi
  • Host Response and Inflammation
    Perturbation of the Small Intestine Microbial Ecology by Streptomycin Alters Pathology in a Salmonella enterica Serovar Typhimurium Murine Model of Infection
    Cherilyn D. Garner, Dionysios A. Antonopoulos, Bettina Wagner, Gerald E. Duhamel, Ivan Keresztes, Deborah A. Ross, Vincent B. Young, Craig Altier
  • Host Response and Inflammation
    Lipopolysaccharide-Trap-Fc, a Multifunctional Agent To Battle Gram-Negative Bacteria
    Philipp Groß, Katharina Brandl, Christine Dierkes, Jürgen Schölmerich, Bernd Salzberger, Thomas Glück, Werner Falk
  • Host Response and Inflammation
    The Capsule-Encoding viaB Locus Reduces Intestinal Inflammation by a Salmonella Pathogenicity Island 1-Independent Mechanism
    Takeshi Haneda, Sebastian E. Winter, Brian P. Butler, R. Paul Wilson, Çagla Tükel, Maria G. Winter, Ivan Godinez, Renée M. Tsolis, Andreas J. Bäumler
  • Host Response and Inflammation | Spotlight
    The K5 Capsule of Escherichia coli Strain Nissle 1917 Is Important in Mediating Interactions with Intestinal Epithelial Cells and Chemokine Induction
    Mohamed Hafez, Kelly Hayes, Marie Goldrick, Geoff Warhurst, Richard Grencis, Ian S. Roberts
  • Host Response and Inflammation
    Natural Antibody Contributes to Host Defense against an Attenuated Brucella abortus virB Mutant
    Hortensia G. Rolán, Mariana N. Xavier, Renato L. Santos, Renée M. Tsolis
  • Host Response and Inflammation
    Listeria monocytogenes 6-Phosphogluconolactonase Mutants Induce Increased Activation of a Host Cytosolic Surveillance Pathway
    Gregory T. Crimmins, Michael W. Schelle, Anat A. Herskovits, Peggy P. Ni, Benjamin C. Kline, Nicole Meyer-Morse, Anthony T. Iavarone, Daniel A. Portnoy
  • Host Response and Inflammation
    Distinct Roles of CD28- and CD40 Ligand-Mediated Costimulation in the Development of Protective Immunity and Pathology during Chlamydia muridarum Urogenital Infection in Mice
    Lili Chen, Wen Cheng, Pooja Shivshankar, Lei Lei, Xiaoyun Zhang, Yimou Wu, I-Tien Yeh, Guangming Zhong

Fungal and Parasitic Infections

  • Fungal and Parasitic Infections
    Glyceraldehyde-3-Phosphate Dehydrogenase Is a Surface-Associated, Fibronectin-Binding Protein of Trichomonas vaginalis
    A. Lama, A. Kucknoor, V. Mundodi, J. F. Alderete
  • Fungal and Parasitic Infections
    Surfactant Protein D Increases Phagocytosis of Hypocapsular Cryptococcus neoformans by Murine Macrophages and Enhances Fungal Survival
    Scarlett Geunes-Boyer, Timothy N. Oliver, Guilhem Janbon, Jennifer K. Lodge, Joseph Heitman, John R. Perfect, Jo Rae Wright
  • Fungal and Parasitic Infections
    Endothelial Nitric Oxide Synthase Gene Polymorphisms and Plasmodium falciparum Infection in Indian Adults
    Gunanidhi Dhangadamajhi, Biranchi N. Mohapatra, Shantanu K. Kar, Manoranjan Ranjit
  • Fungal and Parasitic Infections
    Distinct Roles for MyD88 and Toll-Like Receptor 2 during Leishmania braziliensis Infection in Mice
    Diego A. Vargas-Inchaustegui, Wendy Tai, Lijun Xin, Alison E. Hogg, David B. Corry, Lynn Soong
  • Fungal and Parasitic Infections
    Use of l-Proline and ATP Production by Trypanosoma cruzi Metacyclic Forms as Requirements for Host Cell Invasion
    Rafael Miyazawa Martins, Charles Covarrubias, Robert Galvez Rojas, Ariel Mariano Silber, Nobuko Yoshida
  • Fungal and Parasitic Infections | Spotlight
    Cellular Tumor Necrosis Factor, Gamma Interferon, and Interleukin-6 Responses as Correlates of Immunity and Risk of Clinical Plasmodium falciparum Malaria in Children from Papua New Guinea
    Leanne J. Robinson, Marthe C. D'Ombrain, Danielle I. Stanisic, Jack Taraika, Nicholas Bernard, Jack S. Richards, James G. Beeson, Livingstone Tavul, Pascal Michon, Ivo Mueller, Louis Schofield
  • Fungal and Parasitic Infections
    Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans
    Akiko Miyazato, Kiwamu Nakamura, Natsuo Yamamoto, Héctor M. Mora-Montes, Misuzu Tanaka, Yuzuru Abe, Daiki Tanno, Ken Inden, Xiao Gang, Keiko Ishii, Kiyoshi Takeda, Shizuo Akira, Shinobu Saijo, Yoichiro Iwakura, Yoshiyuki Adachi, Naohito Ohno, Kotaro Mitsutake, Neil A. R. Gow, Mitsuo Kaku, Kazuyoshi Kawakami

Microbial Immunity and Vaccines

  • Microbial Immunity and Vaccines | Spotlight
    Anti-Alpha-Hemolysin Monoclonal Antibodies Mediate Protection against Staphylococcus aureus Pneumonia
    Brook E. Ragle, Juliane Bubeck Wardenburg
  • Microbial Immunity and Vaccines
    Proteomics-Based Identification of Anchorless Cell Wall Proteins as Vaccine Candidates against Staphylococcus aureus
    Eva Glowalla, Bettina Tosetti, Martin Krönke, Oleg Krut
  • Microbial Immunity and Vaccines
    Bivalent Recombinant Vaccine for Botulinum Neurotoxin Types A and B Based on a Polypeptide Comprising Their Effector and Translocation Domains That Is Protective against the Predominant A and B Subtypes
    Clifford Shone, Heidi Agostini, Joanna Clancy, Mili Gu, Huei-Hsiung Yang, Yanfang Chu, Virginia Johnson, Makie Taal, Joanna McGlashan, John Brehm, Xiaomi Tong
  • Microbial Immunity and Vaccines
    Sortase A Confers Protection against Streptococcus pneumoniae in Mice
    Claudia Gianfaldoni, Silvia Maccari, Laura Pancotto, Giacomo Rossi, Markus Hilleringmann, Werner Pansegrau, Antonia Sinisi, Monica Moschioni, Vega Masignani, Rino Rappuoli, Giuseppe Del Giudice, Paolo Ruggiero
  • Microbial Immunity and Vaccines
    M-Cell Targeting of Whole Killed Bacteria Induces Protective Immunity against Gastrointestinal Pathogens
    Yok-Teng Chionh, Janet L. K. Wee, Alison L. Every, Garrett Z. Ng, Philip Sutton
  • Microbial Immunity and Vaccines
    Expression of B-Cell Activating Factor Enhances Protective Immunity of a Vaccine against Pseudomonas aeruginosa
    Christine Tertilt, Ju Joh, Anja Krause, Paigee Chou, Kristin Schneeweiss, Ronald G. Crystal, Stefan Worgall
  • Microbial Immunity and Vaccines
    Role for Toll-Like Receptor 2 in the Immune Response to Streptococcus pneumoniae Infection in Mouse Otitis Media
    Fengchan Han, Heping Yu, Cong Tian, Shengli Li, Michael R. Jacobs, Cindy Benedict-Alderfer, Qing Y. Zheng

Letter To The Editor

  • Letter to the Editor
    NIH Peer Review Reform
    Marc C. Torjman
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Infection and Immunity: 77 (7)

In This Issue

volume 77, issue 7
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  • Pathogenic Mannheimia haemolytica Invades Differentiated Bovine Airway Epithelial Cells
  • Fitness Trade-Offs Resulting from Bacteriophage Resistance Potentiate Synergistic Antibacterial Strategies
  • An Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector
  • Success of Escherichia coli O25b:H4 Sequence Type 131 Clade C Associated with a Decrease in Virulence
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