Cover photograph (Copyright © 2010, American Society for Microbiology. All Rights Reserved.): Candida albicans infection of a rat denture results in biofilm growth and mimics denture stomatitis. (Upper left) Scanning electron micrograph shows a biofilm composed of hyphae, yeast cells, host cells, bacteria, and extracellular matrix attached to the denture surface. (Upper right) Inoculation of an acrylic rat denture. (Lower left) Gomori's methenamine silver stain demonstrates tissue invasion by Candida hyphae. (Lower right) Candida cells are stained with calcofluor white (blue) and bacteria are stained with SYTO 9 (yellow). (See related article on p. 3650.)