Infection and Immunity: 80 (12)

December 1, 2012; Volume 80,Issue 12

Editorial

Free

Editorial
Acknowledgment of Ad Hoc Reviewers

Spotlight

Free

Spotlight
Articles of Significant Interest Selected from This Issue by the Editors

Minireview

Minireview
Antivirulence Genes: Insights into Pathogen Evolution through Gene Loss
Kimberly A. Bliven, Anthony T. Maurelli

Molecular Pathogenesis

Molecular Pathogenesis
Cysteine-Scanning Mutagenesis Supports the Importance of Clostridium perfringens Enterotoxin Amino Acids 80 to 106 for Membrane Insertion and Pore Formation
Jianwu Chen, James R. Theoret, Archana Shrestha, James G. Smedley, Bruce A. McClane
Molecular Pathogenesis
The Hydroxamate Siderophore Rhequichelin Is Required for Virulence of the Pathogenic Actinomycete Rhodococcus equi
Raúl Miranda-CasoLuengo, Garry B. Coulson, Aleksandra Miranda-CasoLuengo, José A. Vázquez-Boland, Mary K. Hondalus, Wim G. Meijer
Molecular Pathogenesis
Escherichia coli Isolates That Carry vat, fyuA, chuA, and yfcV Efficiently Colonize the Urinary Tract
Rachel R. Spurbeck, Paul C. Dinh, Seth T. Walk, Ann E. Stapleton, Thomas M. Hooton, Lisa K. Nolan, Kwang Sik Kim, James R. Johnson, Harry L. T. Mobley
Molecular Pathogenesis
YbcL of Uropathogenic Escherichia coli Suppresses Transepithelial Neutrophil Migration
Megan E. Lau, Jennifer A. Loughman, David A. Hunstad
Molecular Pathogenesis
Analysis of the Mechanisms That Underlie Absorption of Botulinum Toxin by the Inhalation Route
Fetweh H. Al-Saleem, Denise M. Ancharski, Suresh G. Joshi, M. Elias, Ajay Singh, Zidoon Nasser, Lance L. Simpson
Molecular Pathogenesis
Virulence Phenotypes of Legionella pneumophila Associated with Noncoding RNA lpr0035
Deepak Jayakumar, Julie V. Early, Howard M. Steinman
Molecular Pathogenesis
Transposon Mutagenesis of Salmonella enterica Serovar Enteritidis Identifies Genes That Contribute to Invasiveness in Human and Chicken Cells and Survival in Egg Albumen
Devendra H. Shah, Xiaohui Zhou, Hye-Young Kim, Douglas R. Call, Jean Guard
Molecular Pathogenesis
Cyclic Di-GMP Stimulates Biofilm Formation and Inhibits Virulence of Francisella novicida
Xhavit Zogaj, Geoff C. Wyatt, Karl E. Klose
Molecular Pathogenesis
Expression of STM4467-Encoded Arginine Deiminase Controlled by the STM4463 Regulator Contributes to Salmonella enterica Serovar Typhimurium Virulence
Younho Choi, Jeongjoon Choi, Eduardo A. Groisman, Dong-Hyun Kang, Dongwoo Shin, Sangryeol Ryu
Molecular Pathogenesis
Thiol Peroxidase Is an Important Component of Streptococcus pneumoniae in Oxygenated Environments
Barak Hajaj, Hasan Yesilkaya, Rachel Benisty, Maayan David, Peter W. Andrew, Nurith Porat
Molecular Pathogenesis
Interplay between the QseC and QseE Bacterial Adrenergic Sensor Kinases in Salmonella enterica Serovar Typhimurium Pathogenesis
Cristiano G. Moreira, Vanessa Sperandio
Molecular Pathogenesis
The Vibrio cholerae trh Gene Is Coordinately Regulated In Vitro with Type III Secretion System Genes by VttR_A/VttR_B but Does Not Contribute to Caco2-BBE Cell Cytotoxicity
Kelly A. Miller, Elaine Hamilton, Michelle Dziejman

Cellular Microbiology: Pathogen-host Cell Molecular Interactions

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Enteropathogenic Escherichia coli and Vaccinia Virus Do Not Require the Family of WASP-Interacting Proteins for Pathogen-Induced Actin Assembly
John J. Garber, Fuminao Takeshima, Inés M. Antón, Michiko K. Oyoshi, Anna Lyubimova, Archana Kapoor, Tomoyuki Shibata, Feng Chen, Frederick W. Alt, Raif S. Geha, John M. Leong, Scott B. Snapper
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Campylobacter jejuni Outer Membrane Vesicles Play an Important Role in Bacterial Interactions with Human Intestinal Epithelial Cells
Abdi Elmi, Eleanor Watson, Pamela Sandu, Ozan Gundogdu, Dominic C. Mills, Neil F. Inglis, Erin Manson, Lisa Imrie, Mona Bajaj-Elliott, Brendan W. Wren, David G. E. Smith, Nick Dorrell
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Involvement of Signal Regulatory Protein α, a Negative Regulator of Toll-Like Receptor Signaling, in Impairing the MyD88-Independent Pathway and Intracellular Killing of Burkholderia pseudomallei-Infected Mouse Macrophages
Pankaj Baral, Pongsak Utaisincharoen
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Reversible Inhibition of Chlamydia trachomatis Infection in Epithelial Cells Due to Stimulation of P2X₄ Receptors
Matthew A. Pettengill, Camila Marques-da-Silva, Maria Luisa Avila, Suellen d'Arc dos Santos Oliveira, Verissa W. Lam, Ikechukwu Ollawa, Ali A. Abdul Sater, Robson Coutinho-Silva, Georg Häcker, David M. Ojcius
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Role for Telomerase in Listeria monocytogenes Infection
Ascel Samba-Louaka, Fabrizia Stavru, Pascale Cossart
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Bacillus anthracis Lethal Toxin Reduces Human Alveolar Epithelial Barrier Function
Marybeth Langer, Elizabeth Stewart Duggan, John Leland Booth, Vineet Indrajit Patel, Ryan A. Zander, Robert Silasi-Mansat, Vijay Ramani, Tibor Zoltan Veres, Frauke Prenzler, Katherina Sewald, Daniel M. Williams, Kenneth Mark Coggeshall, Shanjana Awasthi, Florea Lupu, Dennis Burian, Jimmy Dale Ballard, Armin Braun, Jordan Patrick Metcalf

Bacterial Infections

Bacterial Infections
Meningococcal PilV Potentiates Neisseria meningitidis Type IV Pilus-Mediated Internalization into Human Endothelial and Epithelial Cells
Hideyuki Takahashi, Tatsuo Yanagisawa, Kwang Sik Kim, Shigeyuki Yokoyama, Makoto Ohnishi
Bacterial Infections
Immune Modulation by Group B Streptococcus Influences Host Susceptibility to Urinary Tract Infection by Uropathogenic Escherichia coli
Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, Scott J. Hultgren, Amanda L. Lewis
Bacterial Infections
Crucial Role of Gamma Interferon-Producing CD4⁺ Th1 Cells but Dispensable Function of CD8⁺ T Cell, B Cell, Th2, and Th17 Responses in the Control of Brucella melitensis Infection in Mice
Marie-Alice Vitry, Carl De Trez, Stanislas Goriely, Laure Dumoutier, Shizuo Akira, Bernhard Ryffel, Yves Carlier, Jean-Jacques Letesson, Eric Muraille
Bacterial Infections
FMS-Like Tyrosine Kinase 3 Ligand Treatment of Mice Aggravates Acute Lung Injury in Response to Streptococcus pneumoniae: Role of Pneumolysin
Christina Brumshagen, Regina Maus, Andrea Bischof, Bianca Ueberberg, Jennifer Bohling, John J. Osterholzer, Abiodun D. Ogunniyi, James C. Paton, Tobias Welte, Ulrich A. Maus
Bacterial Infections
Bordetella parapertussis Survives the Innate Interaction with Human Neutrophils by Impairing Bactericidal Trafficking inside the Cell through a Lipid Raft-Dependent Mechanism Mediated by the Lipopolysaccharide O Antigen
Juan Gorgojo, Yanina Lamberti, Hugo Valdez, Eric T. Harvill, Maria Eugenia Rodríguez
Bacterial Infections
Genotypic and Phenotypic Characterization of Clostridium perfringens Isolates from Darmbrand Cases in Post-World War II Germany
Menglin Ma, Jihong Li, Bruce A. McClane
Bacterial Infections
In Vivo Sequence Variation in HopZ, a Phase-Variable Outer Membrane Protein of Helicobacter pylori
Lynn Kennemann, Birgit Brenneke, Sönke Andres, Lars Engstrand, Thomas F. Meyer, Toni Aebischer, Christine Josenhans, Sebastian Suerbaum
Bacterial Infections
Insulin Treatment Directly Restores Neutrophil Phagocytosis and Bactericidal Activity in Diabetic Mice and Thereby Improves Surgical Site Staphylococcus aureus Infection
Hidekazu Yano, Manabu Kinoshita, Keiichi Fujino, Masahiro Nakashima, Yoritsuna Yamamoto, Hiromi Miyazaki, Koji Hamada, Satoshi Ono, Keiichi Iwaya, Daizoh Saitoh, Shuhji Seki, Yuji Tanaka
Bacterial Infections
Contribution of Adenosine A_2B Receptors in Clostridium difficile Intoxication and Infection
Cirle A. Warren, Yuesheng Li, Gina M. Calabrese, Rosemayre S. Freire, Snjezana Zaja-Milatovic, Edward van Opstal, Robert A. Figler, Joel Linden, Richard L. Guerrant

Host Response and Inflammation

Host Response and Inflammation
Inflammatory Monocyte Recruitment Is Regulated by Interleukin-23 during Systemic Bacterial Infection
Mohanalaxmi Indramohan, Amy N. Sieve, Timothy J. Break, Rance E. Berg
Host Response and Inflammation
Susceptibility to Progressive Cryptococcus neoformans Pulmonary Infection Is Regulated by Loci on Mouse Chromosomes 1 and 9
Scott F. Carroll, Erin I. Lafferty, Adam Flaczyk, T. Mary Fujiwara, Robert Homer, Kenneth Morgan, J C. Loredo-Osti, Salman T. Qureshi
Host Response and Inflammation
Nocardia farcinica Activates Human Dendritic Cells and Induces Secretion of Interleukin-23 (IL-23) Rather than IL-12p70
Martin Eisenblätter, Ariane Buchal, Hermine Gayum, Edith Jasny, Pablo Renner Viveros, Timo Ulrichs, Thomas Schneider, Ralf R. Schumann, Janine Zweigner, Ralf Ignatius
Host Response and Inflammation
Pertussis Toxin Exacerbates and Prolongs Airway Inflammatory Responses during Bordetella pertussis Infection
Carey E. Connelly, Yezhou Sun, Nicholas H. Carbonetti
Host Response and Inflammation
Systemic Macrophage Depletion Inhibits Helicobacter bilis-Induced Proinflammatory Cytokine-Mediated Typhlocolitis and Impairs Bacterial Colonization Dynamics in a BALB/c Rag2 ^−/− Mouse Model of Inflammatory Bowel Disease
Sureshkumar Muthupalani, Zhongming Ge, Yan Feng, Barry Rickman, Melissa Mobley, Amanda McCabe, Nico Van Rooijen, James G. Fox
Host Response and Inflammation
Microbial Amyloids Induce Interleukin 17A (IL-17A) and IL-22 Responses via Toll-Like Receptor 2 Activation in the Intestinal Mucosa
Jessalyn H. Nishimori, Tiffanny N. Newman, Gertrude O. Oppong, Glenn J. Rapsinski, Jui-Hung Yen, Steven G. Biesecker, R. Paul Wilson, Brian P. Butler, Maria G. Winter, Renee M. Tsolis, Doina Ganea, Çagla Tükel
Host Response and Inflammation
Enterotoxigenic Escherichia coli Prevents Host NF-κB Activation by Targeting IκBα Polyubiquitination
Xiaogang Wang, Philip R. Hardwidge
Host Response and Inflammation
Haemophilus ducreyi-Induced Interleukin-10 Promotes a Mixed M1 and M2 Activation Program in Human Macrophages
Wei Li, Barry P. Katz, Stanley M. Spinola
Host Response and Inflammation
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels
Elly O. Munde, Winnie A. Okeyo, Samwel B. Anyona, Evans Raballah, Stephen Konah, Wilson Okumu, Lilian Ogonda, John Vulule, Collins Ouma
Host Response and Inflammation
Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure
Simon A. Hirota, Vadim Iablokov, Sarah E. Tulk, L. Patrick Schenck, Helen Becker, Jimmie Nguyen, Samir Al Bashir, Tanis C. Dingle, Austin Laing, Jianrui Liu, Yan Li, Jeff Bolstad, George L. Mulvey, Glen D. Armstrong, Wallace K. MacNaughton, Daniel A. Muruve, Justin A. MacDonald, Paul L. Beck
Host Response and Inflammation
Interleukin 13 Exposure Enhances Vitamin D-Mediated Expression of the Human Cathelicidin Antimicrobial Peptide 18/LL-37 in Bronchial Epithelial Cells
J. A. Schrumpf, M. A. J. A. van Sterkenburg, R. M. Verhoosel, S. Zuyderduyn, P. S. Hiemstra

Fungal and Parasitic Infections

Open Access

Fungal and Parasitic Infections
Dectin-1 Is Not Required for Controlling Candida albicans Colonization of the Gastrointestinal Tract
Simon Vautier, Rebecca A. Drummond, Pierre Redelinghuys, Graeme I. Murray, Donna M. MacCallum, Gordon D. Brown
Fungal and Parasitic Infections
Transient Deficiency of Dendritic Cells Results in Lack of a Merozoite Surface Protein 1-Specific CD4 T Cell Response during Peak Plasmodium chabaudi Blood-Stage Infection
Anne-Marit Sponaas, Nikolai Belyaev, Mika Falck-Hansen, Alexandre Potocnik, Jean Langhorne
Open Access

Fungal and Parasitic Infections
Progressive Cross-Reactivity in IgE Responses: an Explanation for the Slow Development of Human Immunity to Schistosomiasis?
Colin M. Fitzsimmons, Frances M. Jones, Angela Pinot de Moira, Anna V. Protasio, Jamal Khalife, Harriet A. Dickinson, Edridah M. Tukahebwa, David W. Dunne
Fungal and Parasitic Infections
Impaired Innate Immunity in Mice Deficient in Interleukin-1 Receptor-Associated Kinase 4 Leads to Defective Type 1 T Cell Responses, B Cell Expansion, and Enhanced Susceptibility to Infection with Toxoplasma gondii
Samantha R. Béla, Míriam S. Dutra, Ernest Mui, Alexandre Montpetit, Fernanda S. Oliveira, Sérgio C. Oliveira, Rosa M. E. Arantes, Lis R. Antonelli, Rima McLeod, Ricardo T. Gazzinelli
Fungal and Parasitic Infections
Feed-Forward Regulation of Phagocytosis by Entamoeba histolytica
Adam Sateriale, Archana Vaithilingam, Liam Donnelly, Peter Miller, Christopher D. Huston

Microbial Immunity and Vaccines

Microbial Immunity and Vaccines
Antigenic Characterization of an Intrinsically Unstructured Protein, Plasmodium falciparum Merozoite Surface Protein 2
Christopher G. Adda, Christopher A. MacRaild, Linda Reiling, Kaye Wycherley, Michelle J. Boyle, Vivian Kienzle, Paul Masendycz, Michael Foley, James G. Beeson, Raymond S. Norton, Robin F. Anders

Author's Correction

Author's Correction
The Vibrio cholerae Pst2 Phosphate Transport System Is Upregulated in Biofilms and Contributes to Biofilm-Induced Hyperinfectivity
Benjamin Mudrak, Rita Tamayo

Main menu

User menu

Search

Table of Contents

Editorial

Spotlight

Minireview

Molecular Pathogenesis

Cellular Microbiology: Pathogen-host Cell Molecular Interactions

Bacterial Infections

Host Response and Inflammation

Fungal and Parasitic Infections

Microbial Immunity and Vaccines

Author's Correction

In This Issue

Jump to