Cover photograph (Copyright © 2012, American Society for Microbiology. All Rights Reserved.): Hematoxylin-eosin-stained intestinal tissue section from a neutrophil-depleted mouse infected with nontoxigenic Vibrio cholerae for 6 h. The study demonstrates that neutrophils are required to contain the infection to the small intestine. (Photo taken by G. Kenneth Haines, Yale University.) (See related article on p. 2905.)