Cover photograph (Copyright © 2013, American Society for Microbiology. All Rights Reserved.): Residues in the outer membrane porin PorB of Neisseria gonorrhoeae strain FA1090 that are involved in binding to the complement regulatory factors C4bp and factor H. The structure of the FA1090 PorB monomer was predicted using I-TASSER and visualized using DeepView Swiss-PdbViewer (v. 4.1). Extracellular loops 4 through 7 are labeled. (Left) Regions of the protein involved in C4bp binding are labeled in red in the context of the predicted structure. (Right) Regions of the protein involved in factor H binding are labeled in blue, and regions labeled in purple show an intermediate factor H binding phenotype when mutated. (See related article on p. 4383.)