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Microbial Immunity and Vaccines

A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2

Jacqueline M. Tremblay, Jean Mukherjee, Clinton E. Leysath, Michelle Debatis, Kwasi Ofori, Karen Baldwin, Courtney Boucher, Rachel Peters, Gillian Beamer, Abhineet Sheoran, Daniela Bedenice, Saul Tzipori, Charles B. Shoemaker
S. R. Blanke, Editor
Jacqueline M. Tremblay
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Jean Mukherjee
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Clinton E. Leysath
bNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
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Michelle Debatis
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Kwasi Ofori
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Karen Baldwin
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Courtney Boucher
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Rachel Peters
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Gillian Beamer
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Abhineet Sheoran
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Daniela Bedenice
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Saul Tzipori
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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Charles B. Shoemaker
aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
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S. R. Blanke
Roles: Editor
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DOI: 10.1128/IAI.01033-13
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Article Information

DOI 
https://doi.org/10.1128/IAI.01033-13
PubMed 
24082082

Published By 
American Society for Microbiology Journals
History 
  • Received August 21, 2013
  • Accepted September 23, 2013
  • Published online November 13, 2013.

Copyright & Usage 
Copyright © 2013, American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • S. R. Blanke, Editor

Article Versions

  • Accepted Manuscript version (September 30, 2013).
  • You are viewing the most recent version of this article.

Author Information

  1. Jacqueline M. Tremblaya,
  2. Jean Mukherjeea,
  3. Clinton E. Leysathb,
  4. Michelle Debatisa,
  5. Kwasi Oforia,
  6. Karen Baldwina,
  7. Courtney Bouchera,
  8. Rachel Petersa,
  9. Gillian Beamera,
  10. Abhineet Sheorana,
  11. Daniela Bedenicea,
  12. Saul Tziporia and
  13. Charles B. Shoemakera
  1. aDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA
  2. bNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
  • Address correspondence to Charles B. Shoemaker, charles.shoemaker{at}tufts.edu.
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A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2
Jacqueline M. Tremblay, Jean Mukherjee, Clinton E. Leysath, Michelle Debatis, Kwasi Ofori, Karen Baldwin, Courtney Boucher, Rachel Peters, Gillian Beamer, Abhineet Sheoran, Daniela Bedenice, Saul Tzipori, Charles B. Shoemaker
Infection and Immunity Nov 2013, 81 (12) 4592-4603; DOI: 10.1128/IAI.01033-13

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A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2
Jacqueline M. Tremblay, Jean Mukherjee, Clinton E. Leysath, Michelle Debatis, Kwasi Ofori, Karen Baldwin, Courtney Boucher, Rachel Peters, Gillian Beamer, Abhineet Sheoran, Daniela Bedenice, Saul Tzipori, Charles B. Shoemaker
Infection and Immunity Nov 2013, 81 (12) 4592-4603; DOI: 10.1128/IAI.01033-13
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