Cover photograph (Copyright © 2013, American Society for Microbiology.): Scanning electron micrograph depicting Candida parapsilosis yeast (green) adhering to a human endothelial monolayer (pink) and being enveloped by thin membrane extensions from endothelial cells. Endocytosis of Candida by endothelial cells may represent a means of traversal of the blood vessel wall by yeast during disseminated candidiasis, and the actin nucleation promotion factor N-WASP may play a key role in the process. (See related article on p. 2777.