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Molecular Pathogenesis | Spotlight

Cell Invasion and Pyruvate Oxidase-Derived H2O2 Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing

Terry Brissac, Anukul T. Shenoy, LaDonna A. Patterson, Carlos J. Orihuela
Liise-anne Pirofski, Editor
Terry Brissac
aDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Anukul T. Shenoy
aDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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LaDonna A. Patterson
aDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Carlos J. Orihuela
aDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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  • ORCID record for Carlos J. Orihuela
Liise-anne Pirofski
Albert Einstein College of Medicine
Roles: Editor
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DOI: 10.1128/IAI.00569-17
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Article Information

DOI 
https://doi.org/10.1128/IAI.00569-17
PubMed 
29061707

Published By 
American Society for Microbiology Journals
History 
  • Received August 7, 2017
  • Returned for modification September 10, 2017
  • Accepted October 17, 2017
  • Published online December 19, 2017.

Copyright & Usage 
Copyright © 2017 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Liise-anne Pirofski, Editor, Albert Einstein College of Medicine

Article Versions

  • Accepted Manuscript version (October 23, 2017).
  • You are viewing the most recent version of this article.

Author Information

  1. Terry Brissaca,
  2. Anukul T. Shenoya,
  3. LaDonna A. Pattersona and
  4. Carlos J. Orihuelaa
  1. aDepartment of Microbiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
  • Address correspondence to Carlos J. Orihuela, corihuel{at}uab.edu.
  • Citation Brissac T, Shenoy AT, Patterson LA, Orihuela CJ. 2018. Cell invasion and pyruvate oxidase-derived H2O2 are critical for Streptococcus pneumoniae-mediated cardiomyocyte killing. Infect Immun 86:e00569-17. https://doi.org/10.1128/IAI.00569-17.

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Cell Invasion and Pyruvate Oxidase-Derived H2O2 Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing
Terry Brissac, Anukul T. Shenoy, LaDonna A. Patterson, Carlos J. Orihuela
Infection and Immunity Dec 2017, 86 (1) e00569-17; DOI: 10.1128/IAI.00569-17

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Cell Invasion and Pyruvate Oxidase-Derived H2O2 Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing
Terry Brissac, Anukul T. Shenoy, LaDonna A. Patterson, Carlos J. Orihuela
Infection and Immunity Dec 2017, 86 (1) e00569-17; DOI: 10.1128/IAI.00569-17
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KEYWORDS

Cardiac acute events
cardiomyocytes
invasive pneumococcal disease
Streptococcus pneumoniae
facultatively intracellular pathogens
oxidative stress

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