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Cellular Microbiology: Pathogen-Host Cell Molecular Interactions

Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2

Romain A. Colas, Anthony W. Ashton, Shankar Mukherjee, Jesmond Dalli, Oscar B. Akide-Ndunge, Huan Huang, Mahalia S. Desruisseaux, Fangxia Guan, Linda A. Jelicks, Fabiane Matos dos Santos, Jyothi Nagajyothi, Michael A. Zingman, Jinet Reyes, Louis M. Weiss, Charles N. Serhan, Herbert B. Tanowitz
Judith A. Appleton, Editor
Romain A. Colas
aCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Anthony W. Ashton
bKolling Institute of Medical Research, Royal North Shore Hospital, St. Leonards, NSW, Australia
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  • ORCID record for Anthony W. Ashton
Shankar Mukherjee
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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Jesmond Dalli
aCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Oscar B. Akide-Ndunge
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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  • ORCID record for Oscar B. Akide-Ndunge
Huan Huang
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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Mahalia S. Desruisseaux
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
dDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
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Fangxia Guan
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
gSchool of Life Sciences, Zhengzhou University, Zhengzhou, China
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Linda A. Jelicks
eDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, New York, USA
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Fabiane Matos dos Santos
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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Jyothi Nagajyothi
fPublic Health Research Institute Center at the International Center for Public Health, New Jersey Medical School—Rutgers, The State University of New Jersey, Rutgers, New Jersey, USA
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Michael A. Zingman
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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Jinet Reyes
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
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Louis M. Weiss
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
dDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
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Charles N. Serhan
aCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
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Herbert B. Tanowitz
cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
dDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
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Judith A. Appleton
Cornell University
Roles: Editor
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DOI: 10.1128/IAI.00688-17
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Article Information

DOI 
https://doi.org/10.1128/IAI.00688-17
PubMed 
29358332

Published By 
American Society for Microbiology Journals
History 
  • Received September 29, 2017
  • Returned for modification October 25, 2017
  • Accepted January 14, 2018
  • Published online March 22, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Judith A. Appleton, Editor, Cornell University

Article Versions

  • Accepted Manuscript version (January 22, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Romain A. Colasa*,
  2. Anthony W. Ashtonb,
  3. Shankar Mukherjeec,
  4. Jesmond Dallia*,
  5. Oscar B. Akide-Ndungec,
  6. Huan Huangc,
  7. Mahalia S. Desruisseauxc,d,
  8. Fangxia Guanc,g,
  9. Linda A. Jelickse,
  10. Fabiane Matos dos Santosc,
  11. Jyothi Nagajyothif,
  12. Michael A. Zingmanc*,
  13. Jinet Reyesc,
  14. Louis M. Weissc,d,
  15. Charles N. Serhana and
  16. Herbert B. Tanowitzc,d
  1. aCenter for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
  2. bKolling Institute of Medical Research, Royal North Shore Hospital, St. Leonards, NSW, Australia
  3. cDepartment of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA
  4. dDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
  5. eDepartment of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, New York, USA
  6. fPublic Health Research Institute Center at the International Center for Public Health, New Jersey Medical School—Rutgers, The State University of New Jersey, Rutgers, New Jersey, USA
  7. gSchool of Life Sciences, Zhengzhou University, Zhengzhou, China
  • Address correspondence to Herbert B. Tanowitz, herbert.tanowitz{at}einstein.yu.edu.
  • ↵* Present address: Romain A. Colas and Jesmond Dalli, Lipid Mediator Unit, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom; Michael A. Zingman, Columbia University College of Physicians and Surgeons, New York, New York, USA.

  • R.A.C. and A.W.A. contributed equally to this work.

  • Citation Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB. 2018. Trypanosoma cruzi produces the specialized proresolving mediators resolvin D1, resolvin D5, and resolvin E2. Infect Immun 86:e00688-17. https://doi.org/10.1128/IAI.00688-17.

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Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2
Romain A. Colas, Anthony W. Ashton, Shankar Mukherjee, Jesmond Dalli, Oscar B. Akide-Ndunge, Huan Huang, Mahalia S. Desruisseaux, Fangxia Guan, Linda A. Jelicks, Fabiane Matos dos Santos, Jyothi Nagajyothi, Michael A. Zingman, Jinet Reyes, Louis M. Weiss, Charles N. Serhan, Herbert B. Tanowitz
Infection and Immunity Mar 2018, 86 (4) e00688-17; DOI: 10.1128/IAI.00688-17

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Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2
Romain A. Colas, Anthony W. Ashton, Shankar Mukherjee, Jesmond Dalli, Oscar B. Akide-Ndunge, Huan Huang, Mahalia S. Desruisseaux, Fangxia Guan, Linda A. Jelicks, Fabiane Matos dos Santos, Jyothi Nagajyothi, Michael A. Zingman, Jinet Reyes, Louis M. Weiss, Charles N. Serhan, Herbert B. Tanowitz
Infection and Immunity Mar 2018, 86 (4) e00688-17; DOI: 10.1128/IAI.00688-17
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    • ABSTRACT
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KEYWORDS

Trypanosoma cruzi
Chagas disease
resolvins
resolvin D1
resolvin D5
resolvin E2
inflammation
immune modulation
eicosanoids
resolvin
host-parasite relationship

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