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Microbial Immunity and Vaccines

MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage

Rajakumar Mandraju, Aakanksha Jain, Yajing Gao, Zhiming Ouyang, Michael V. Norgard, Chandrashekhar Pasare
Andreas J. Bäumler, Editor
Rajakumar Mandraju
aDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Aakanksha Jain
aDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Yajing Gao
aDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Zhiming Ouyang
bDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Michael V. Norgard
bDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Chandrashekhar Pasare
aDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
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Andreas J. Bäumler
University of California, Davis
Roles: Editor
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DOI: 10.1128/IAI.00791-17
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Article Information

DOI 
https://doi.org/10.1128/IAI.00791-17
PubMed 
29507085

Published By 
American Society for Microbiology Journals
History 
  • Received November 2, 2017
  • Returned for modification November 21, 2017
  • Accepted February 28, 2018
  • Published online April 23, 2018.

Copyright & Usage 
Copyright © 2018 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Andreas J. Bäumler, Editor, University of California, Davis

Article Versions

  • Accepted Manuscript version (March 05, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Rajakumar Mandrajua,
  2. Aakanksha Jaina,
  3. Yajing Gaoa,
  4. Zhiming Ouyangb,
  5. Michael V. Norgardb and
  6. Chandrashekhar Pasarea
  1. aDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
  2. bDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
  • Address correspondence to Chandrashekhar Pasare, Chandrashekhar.pasare{at}UTSouthwestern.edu.
  • Citation Mandraju R, Jain A, Gao Y, Ouyang Z, Norgard MV, Pasare C. 2018. MyD88 signaling in T cells is critical for effector CD4 T cell differentiation following a transitional T follicular helper cell stage. Infect Immun 86:e00791-17. https://doi.org/10.1128/IAI.00791-17.

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MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage
Rajakumar Mandraju, Aakanksha Jain, Yajing Gao, Zhiming Ouyang, Michael V. Norgard, Chandrashekhar Pasare
Infection and Immunity Apr 2018, 86 (5) e00791-17; DOI: 10.1128/IAI.00791-17

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MyD88 Signaling in T Cells Is Critical for Effector CD4 T Cell Differentiation following a Transitional T Follicular Helper Cell Stage
Rajakumar Mandraju, Aakanksha Jain, Yajing Gao, Zhiming Ouyang, Michael V. Norgard, Chandrashekhar Pasare
Infection and Immunity Apr 2018, 86 (5) e00791-17; DOI: 10.1128/IAI.00791-17
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KEYWORDS

Borrelia burgdorferi
effector T cells
germinal centers
IL-1
IL-18
MyD88
Tfh cells
Th1/Th17 responses

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