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Bacterial Infections | Spotlight

Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model

Sridevi Ranganathan, Michele Doucet, Christen L. Grassel, BreOnna Delaine-Elias, Nicholas C. Zachos, Eileen M. Barry
Vincent B. Young, Editor
Sridevi Ranganathan
aCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
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Michele Doucet
bDepartment of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Christen L. Grassel
aCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
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BreOnna Delaine-Elias
aCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
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Nicholas C. Zachos
bDepartment of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Eileen M. Barry
aCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
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Vincent B. Young
University of Michigan-Ann Arbor
Roles: Editor
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DOI: 10.1128/IAI.00740-18
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Article Information

DOI 
https://doi.org/10.1128/IAI.00740-18
PubMed 
30642900

Published By 
American Society for Microbiology Journals
History 
  • Received September 30, 2018
  • Returned for modification November 15, 2018
  • Accepted January 6, 2019
  • Published online March 25, 2019.

Copyright & Usage 
Copyright © 2019 Ranganathan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Vincent B. Young, Editor, University of Michigan-Ann Arbor

Article Versions

  • Accepted Manuscript version (January 14, 2019).
  • You are viewing the most recent version of this article.

Author Information

  1. Sridevi Ranganathana,
  2. Michele Doucetb,
  3. Christen L. Grassela,
  4. BreOnna Delaine-Eliasa*,
  5. Nicholas C. Zachosb and
  6. Eileen M. Barrya
  1. aCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
  2. bDepartment of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  • Address correspondence to Eileen M. Barry, embarry{at}som.umaryland.edu.
  • ↵* Present address: BreOnna Delaine-Elias, U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, Maryland, USA.

  • For a companion article on this topic, see https://doi.org/10.1128/IAI.00733-18.

  • Citation Ranganathan S, Doucet M, Grassel CL, Delaine-Elias B, Zachos NC, Barry EM. 2019. Evaluating Shigella flexneri pathogenesis in the human enteroid model. Infect Immun 87:e00740-18. https://doi.org/10.1128/IAI.00740-18.

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Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model
Sridevi Ranganathan, Michele Doucet, Christen L. Grassel, BreOnna Delaine-Elias, Nicholas C. Zachos, Eileen M. Barry
Infection and Immunity Mar 2019, 87 (4) e00740-18; DOI: 10.1128/IAI.00740-18

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Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model
Sridevi Ranganathan, Michele Doucet, Christen L. Grassel, BreOnna Delaine-Elias, Nicholas C. Zachos, Eileen M. Barry
Infection and Immunity Mar 2019, 87 (4) e00740-18; DOI: 10.1128/IAI.00740-18
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    • ABSTRACT
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KEYWORDS

human intestinal enteroids
M cells
S. flexneri pathogenesis
colonoid

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