Cover photograph: Time series capturing the eruption of filamentous uropathogenic Escherichia coli (UPEC) from a remnant bladder epithelial cell, in the microfluidics-based model of cellular infection. The development of intracellular bacterial communities leads to eventual cell disruption and dispersal of many highly filamentous bacteria in response to exposure to urine from a mildly dehydrated individual. (See related article in September 2020, vol. 88, e00884-19.) (Copyright © 2020 American Society for Microbiology. All Rights Reserved.)