Cover photograph: The host glycolytic enzyme aldolase A localizes at Chlamydia trachomatis inclusions. HeLa cells expressing 3×FLAG-tagged aldolase A were infected with a strain of C. trachomatis serovar L2 expressing mCherry (red). Cells were fixed at 24 h postinfection and immunostained with anti-FLAG antibodies (green) to determine the localization of aldolase A within infected cells. Host aldolase A localizes at the C. trachomatis inclusion membrane during infection and confers a developmental advantage to the bacteria. (See related article in December 2020, vol. 88, e00545-20.) (Copyright © 2020 American Society for Microbiology. All Rights Reserved.)