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Host Response and Inflammation

Silencing of Ac45 Simultaneously Inhibits Osteoclast-Mediated Bone Resorption and Attenuates Dendritic Cell-Mediated Inflammation through Impairing Acidification and Cathepsin K Secretion

Wenbin Yang, Zheng Zhu, Longjiang Li, Abigail McVicar, Ning Gao, Lin Wang, Yi-Ping Li, Wei Chen
Marvin Whiteley, Editor
Wenbin Yang
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
bState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Sichuan, People’s Republic of China
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Zheng Zhu
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
cCollege of Stomatology, Nanjing Medical University, Nanjing, People’s Republic of China
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Longjiang Li
bState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Sichuan, People’s Republic of China
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Abigail McVicar
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Ning Gao
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Lin Wang
cCollege of Stomatology, Nanjing Medical University, Nanjing, People’s Republic of China
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Yi-Ping Li
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Wei Chen
aDepartment of Pathology, The School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Marvin Whiteley
Georgia Institute of Technology School of Biological Sciences
Roles: Editor
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DOI: 10.1128/IAI.00436-20
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Silencing of Ac45 Simultaneously Inhibits Osteoclast-Mediated Bone Resorption and Attenuates Dendritic Cell-Mediated Inflammation through Impairing Acidification and Cathepsin K Secretion
Wenbin Yang, Zheng Zhu, Longjiang Li, Abigail McVicar, Ning Gao, Lin Wang, Yi-Ping Li, Wei Chen
Infection and Immunity Dec 2020, 89 (1) e00436-20; DOI: 10.1128/IAI.00436-20

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Silencing of Ac45 Simultaneously Inhibits Osteoclast-Mediated Bone Resorption and Attenuates Dendritic Cell-Mediated Inflammation through Impairing Acidification and Cathepsin K Secretion
Wenbin Yang, Zheng Zhu, Longjiang Li, Abigail McVicar, Ning Gao, Lin Wang, Yi-Ping Li, Wei Chen
Infection and Immunity Dec 2020, 89 (1) e00436-20; DOI: 10.1128/IAI.00436-20
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KEYWORDS

Ac45
adeno-associated virus
bone resorption
inflammation
RNAi silencing
endodontic disease

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