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Fungal and Parasitic Infections

STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway

Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Yu
De'Broski R. Herbert, Editor
Jie Zhao
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
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Xin Liu
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Yao Chen
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Lin-Shuang Zhang
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Ya-Rong Zhang
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Deng-Ren Ji
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Shi-Meng Liu
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Mo-Zhi Jia
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
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Yong-Hong Zhu
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
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Yong-Fen Qi
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
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Feng-Min Lu
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
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Yan-Rong Yu
aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
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  • ORCID record for Yan-Rong Yu
De'Broski R. Herbert
University of Pennsylvania
Roles: Editor
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DOI: 10.1128/IAI.00309-20
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Article Information

DOI 
https://doi.org/10.1128/IAI.00309-20
PubMed 
33257536

Published By 
American Society for Microbiology Journals
History 
  • Received May 26, 2020
  • Returned for modification June 24, 2020
  • Accepted November 15, 2020
  • Published online February 16, 2021.

Copyright & Usage 
Copyright © 2021 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • De'Broski R. Herbert, Editor, University of Pennsylvania

Article Versions

  • Accepted Manuscript version (November 30, 2020).
  • You are viewing the most recent version of this article.

Author Information

  1. Jie Zhaoa,
  2. Xin Liua,b,c,
  3. Yao Chena,b,c,
  4. Lin-Shuang Zhanga,b,c,
  5. Ya-Rong Zhanga,b,c,
  6. Deng-Ren Jia,b,c,
  7. Shi-Meng Liua,b,c,
  8. Mo-Zhi Jiaa,
  9. Yong-Hong Zhua,
  10. Yong-Fen Qia,b,c,
  11. Feng-Min Lua and
  12. Yan-Rong Yua
  1. aDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing, China
  2. bKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing, China
  3. cLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing, China
  • Address correspondence to Yan-Rong Yu, yuyr{at}bjmu.edu.cn.
  • Citation Zhao J, Liu X, Chen Y, Zhang L-S, Zhang Y-R, Ji D-R, Liu S-M, Jia M-Z, Zhu Y-H, Qi Y-F, Lu F-M, Yu Y-R. 2021. STAT3 promotes schistosome-induced liver injury by inflammation, oxidative stress, proliferation, and apoptosis signal pathway. Infect Immun 89:e00309-20. https://doi.org/10.1128/IAI.00309-20.

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STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway
Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Yu
Infection and Immunity Feb 2021, 89 (3) e00309-20; DOI: 10.1128/IAI.00309-20

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STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway
Jie Zhao, Xin Liu, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Deng-Ren Ji, Shi-Meng Liu, Mo-Zhi Jia, Yong-Hong Zhu, Yong-Fen Qi, Feng-Min Lu, Yan-Rong Yu
Infection and Immunity Feb 2021, 89 (3) e00309-20; DOI: 10.1128/IAI.00309-20
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KEYWORDS

S. japonicum
liver injury
STAT3
inflammation
oxidative stress
proliferation
apoptosis

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