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Infection and Immunity
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Minireview | Spotlight

I’m Infected, Eat Me! Innate Immunity Mediated by Live, Infected Cells Signaling To Be Phagocytosed

Tim Birkle, G. C. Brown
Karen M. Ottemann, Editor
Tim Birkle
aDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom
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G. C. Brown
aDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom
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  • ORCID record for G. C. Brown
Karen M. Ottemann
University of California, Santa Cruz
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DOI: 10.1128/IAI.00476-20
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Article Information

DOI 
https://doi.org/10.1128/IAI.00476-20
PubMed 
33558325

Published By 
American Society for Microbiology Journals
History 
  • Published online April 16, 2021.

Copyright & Usage 
Copyright © 2021 American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • Karen M. Ottemann, Editor, University of California, Santa Cruz

Article Versions

  • Accepted Manuscript version (February 08, 2021).
  • You are viewing the most recent version of this article.

Author Information

  1. Tim Birklea and
  2. G. C. Browna
  1. aDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom
  • Address correspondence to G. C. Brown, gcb3{at}cam.ac.uk.
  • Citation Birkle T, Brown GC. 2021. I'm infected, eat me! Innate immunity mediated by live, infected cells signaling to be phagocytosed. Infect Immun 89:e00476-20. https://doi.org/10.1128/IAI.00476-20.

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I’m Infected, Eat Me! Innate Immunity Mediated by Live, Infected Cells Signaling To Be Phagocytosed
Tim Birkle, G. C. Brown
Infection and Immunity Apr 2021, 89 (5) e00476-20; DOI: 10.1128/IAI.00476-20

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I’m Infected, Eat Me! Innate Immunity Mediated by Live, Infected Cells Signaling To Be Phagocytosed
Tim Birkle, G. C. Brown
Infection and Immunity Apr 2021, 89 (5) e00476-20; DOI: 10.1128/IAI.00476-20
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  • Top
  • Article
    • ABSTRACT
    • INTRODUCTION
    • PATHOGEN DETECTION
    • HOST CELL DEATH INDUCED BY INFECTION
    • PHAGOCYTOSIS OF LIVE CELLS
    • FIND-ME SIGNALS
    • EAT-ME SIGNALS: PHOSPHATIDYLSERINE AND CALRETICULIN
    • DON’T-EAT-ME SIGNALS: CD47, SIALIC ACID, AND MHC-I
    • OPSONINS: MFG-E8, GAL-3, ANTIBODIES, AND COMPLEMENT
    • ANTIGEN PRESENTATION
    • RESISTANCE BY PATHOGENS
    • CONCLUSION
    • ACKNOWLEDGMENTS
    • REFERENCES
    • Author Bios
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

phagocytosis
phagoptosis
infection
immunity
virus
intracellular bacteria

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