TABLE 1.

Lag times and growth rates of iron-starved C. albicans strains incubated in low-iron defined growth medium buffered with HEPES and containing the indicated iron sources

Yeast strainCulture lag time (h) witha:Culture doubling time (h)b with:
No iron sourceFeH4NO8S2 (0.4 μM)HoloTf (0.2 μM)ApoTf (0.2 μM)ApoTf + FCH (0.2 + 0.4 μM)FCH (0.4 μM)No iron sourceFeH4NO8S2 (0.4 μM)HoloTf (0.2 μM)ApoTf (0.2 μM)ApoTf + FCH (0.2 + 0.4 μM)FCH (0.4 μM)
Wild type6445335.81.51.84.31.71.4
ftr1 −/− No growth65733No growth1.910.526.51.81.5
ftr1 −/− + FTR14.5445334.51.51.64.61.71.4
  • a HoloTf, holotransferrin; ApoTf, apotransferrin; FCH, ferrichrome.

  • b Doubling times calculated during the logarithmic phase of growth.