TABLE 2.

Levels of IL-6 and KC within the lung tissue and BALF of BALB/c micea

TreatmentMedian (minimum-maximum) level of:
IL-6 (pg/ml)KC (pg/ml)Total protein (mg/ml)
Lung tissueBALFLung tissueBALFBALF
1 μg WT Ply105 (19-325)*250 (24-1,718)**353 (87-1,117)*40 (29-331)*5 (0.4-6)**
1 μg ΔA146 Ply9 (6-85)7 (5-8)40 (31-172)25 (17-32)0.2 (0.2-0.3)
  • a Results following intranasal treatment are shown. n = 6. Significant increases in WT Ply-treated group versus ΔA146 Ply-treated group are marked with asterisks: *, P < 0.05; **, P < 0.01.