TABLE 2.

Mean cytokine and chemokine levels in BALF

Cytokine or chemokineMouse strainConcn(pg/ml) (mean ± SEM) at the following times postinfectiona:
0 h24 h48 h
IL-12p70bCD1NDcND23 ± 9
C57BL/6NDNDND
TNF-αbCD1ND5 ± 5533 ± 133
C57BL/6NDND356 ± 75
IFN-γbCD1NDND53 ± 35
C57BL/6NDNDND
MCP-1bCD1NDND134 ± 63
C57BL/6NDND110 ± 40
IL-10bCD110 ± 1036 ± 219 ± 7
C57BL/612 ± 1239 ± 118 ± 2
IL-6bCD1ND16 ± 92,187 ± 563
C57BL/6ND5 ± 52,820 ± 358
MIP-2bCD1ND24 ± 92,198 ± 569
C57BL/6ND7 ± 51,821 ± 287
KCdCD1ND32 ± 143,830 ± 679
C57BL/6NDND1,548 ± 352e
  • a The data were obtained using 8 to 10 mice.

  • b Values were determined using a cytometric bead assay (BD Bioscience).

  • c ND, not detected.

  • d Values were determined using an ELISA (R&D Systems).

  • e The value is significantly different (P < 0.05) from the value obtained for KC in CD1 mice at 48 h.