TABLE 1.

Immunoprotective potential of rLigA based on lethality in a hamster modela

Expt and inoculumTotal no. of animalsNo. of animals that survivedb
Expt 1
    rLigA88*
    rGST87
    PBS86
Expt 2
    rLigA55*
    rGST54
Expt 3
    rLigA88*
    rGST74
  • a A chi-square test was performed with Statistix 7.0 software to determine if there was a statistically significant difference in mortality between the control and rLigA-immunized animals from all experiments. A significant difference (P = 0.01) was found, indicating the protective efficacy of rLigA against challenge.

  • b *, no histopathological lesions were found in the rLigA-immunized animals, which is in contrast to results for control groups.