Table 1.

Results of in vitro testing by LDH release from Jurkat E6.1 cellsa

CompoundConcn (mM)No. of replicatesOD
MeanSEM% Change
OHHL0.140.080.0010.4
0.0140.080.0030.3
0.00140.080.001−1.0
0.000140.080.002−0.1
OdDHL0.140.120.004−7.8
0.0140.080.003−0.4
0.00140.080.0010
0.000140.080.0010.4
DMSO0.1b40.080.001−0.8
0.01b40.080.0010
0.001b40.080.001−0.5
0.0001b40.080.0010.1
Cells alone80.080.0010
Lysis control80.580.019−100**
  • a Statistical analysis by one-way analysis of variance of OD data, followed by Dunnett’s test. **,P < 0.01.

  • b Dimethyl sulfoxide (DMSO) control diluted the same as equivalent compound concentrations. No significance was noted with the small changes in calculated viability.