TABLE 3.

Prevalence of nanBand nanC among S. pneumoniae isolates

Isolate groupNo. of isolates with gene/no. total (%)
nanBa,bnanCc,d
Blood76/81 (94)41/81 (51)
Cerebrospinal fluid53/55 (96)38/56 (68)
Total invasive129/136 (95)79/137 (58)
Middle ear94/96 (98)49/99 (50)
Carriage93/99 (94)45/103 (44)
Total noninvasive187/195 (96)94/202 (47)
    Total316/331 (96)173/339 (51)
  • a Total no. does not equal 342. Nine isolates were excluded due to insertion elements within the nanB gene. Two additional strains were excluded because we were unable to confirm the presence of nanB by Southern or dot blot hybridization.

  • b For distribution among sites, P = 0.47; for distribution by invasiveness, P = 0.65.

  • c Three isolates were excluded because we were unable to confirm the presence of nanC by Southern or dot blot hybridization.

  • d For distribution among sites, P = 0.03; for distribution by invasiveness, P = 0.04.