TABLE 4.

Arthritis and carditis scores for mice infected with three strains of spirochetes at varying time points postinoculation

StrainMouse typeMean tibiotarsal arthritis severity (range, 0 to 3) ± SD on day:Mean arthritis prevalence (range, 0 to 2) ± SD on day:Carditis prevalence (no. positive/no. examined) on day:
153060153060153060
MI-A3C3H01.0 ± 00.8 ± 0.801.0 ± 00.6 ± 0.55/55/51/5
SCID1.3 ± 0.4a2.6 ± 0.5a3.0 ± 0a2.0 ± 0a2.0 ± 0a2.0 ± 0a2/55/55/5
A3-pB22C3H000.4 ± 0.5000.4 ± 0.50/50/50/5
SCID0b0.8 ± 0.4a,b2.3 ± 0.4a,b0.8 ± 0.4a,b1.4 ± 0.5a1.8 ± 0.4a5/55/55/5
A3-pB22-FAC3H0000000/50/50/5
SCID0.4 ± 0.50.9 ± 0.6b2.2 ± 0.4a,b1.4 ± 0.5a1.3 ± 0.961.8 ± 0.4a4/54/45/5
  • a The mean for SCID mice was significantly different from that for C3H mice for a given strain (P ≤ 0.05).

  • b The mean for SCID mice given the A3-pB22 or A3-pB22-FA strain was significantly different from that for SCID mice given the MI-A3 strain (P ≤ 0.05).