TABLE 4.

Cell surface and secreted bacterial molecular chaperones

BacteriumMolecular chaperoneCell surface or secretedLigandBiological activityReference(s)
A. actinomycetemcomitans Cpn60Both?Osteolytic factor and cytolytic factor 51, 85
Bartonella bacilliformis Cpn60SecretedMitogen 118
Borrelia burgdorferi Cpn60Cell surfaceGlycosphingolipidAdhesin 83, 160
Clostridium difficile Cpn60Cell surface?Adhesin 65
Coxiella burnetti Hsp70Cell surface 110
Enteropathogenic E. coliHsp70Cell surfaceSulfogalactosyl-ceramideAdhesin 24
Haemophilus ducreyi Cpn60Cell surface?Adhesin 43
Helicobacter pylori Hsp20Cell surface? 27
Helicobacter pylori Cpn60Cell surface?Adhesin 82, 183-185
Helicobacter pylori Hsp70Cell surfaceSulfatidesAdhesin 73
Helicobacter pylori PPISecreted?Induces epithelial cell apoptosis 7
Legionella pneumophila Cpn60, Hsp70Cell surface?Adhesin 46, 47, 68
Mycobacterium avium Cpn60Cell surface?Adhesin 33, 143
Mycobacterium avium Hsp70Cell surface?Possible adhesin 144
Mycobacterium smegmatis Cpn60Cell surface? 31
Rickettsia prowazekii PPICell surface? 46
Salmonella enterica serovar TyphimuriumCpn60Cell surfaceMucusAdhesin 32