TABLE 4.

Cell surface and secreted bacterial molecular chaperones

BacteriumMolecular chaperoneCell surface or secretedLigandBiological activityReference(s)
A. actinomycetemcomitansCpn60Both?Osteolytic factor and cytolytic factor51, 85
Bartonella bacilliformisCpn60SecretedMitogen118
Borrelia burgdorferiCpn60Cell surfaceGlycosphingolipidAdhesin83, 160
Clostridium difficileCpn60Cell surface?Adhesin65
Coxiella burnettiHsp70Cell surface110
Enteropathogenic E. coliHsp70Cell surfaceSulfogalactosyl-ceramideAdhesin24
Haemophilus ducreyiCpn60Cell surface?Adhesin43
Helicobacter pyloriHsp20Cell surface?27
Helicobacter pyloriCpn60Cell surface?Adhesin82, 183-185
Helicobacter pyloriHsp70Cell surfaceSulfatidesAdhesin73
Helicobacter pyloriPPISecreted?Induces epithelial cell apoptosis7
Legionella pneumophilaCpn60, Hsp70Cell surface?Adhesin46, 47, 68
Mycobacterium aviumCpn60Cell surface?Adhesin33, 143
Mycobacterium aviumHsp70Cell surface?Possible adhesin144
Mycobacterium smegmatisCpn60Cell surface?31
Rickettsia prowazekiiPPICell surface?46
Salmonella enterica serovar TyphimuriumCpn60Cell surfaceMucusAdhesin32