TABLE 2.

Contributions of the Sit and MntH systems to oxidative stress survival in S. flexneri

StrainZone of growth inhibition (mm)a on the following medium
L agar with:T agar with:
H2O2bPMScMDcH2O2PMSMD
SM100 (wild type)22 ± 034 ± 222 ± 038 ± 347 ± 127 ± 4
SM166 (sit::cam)20 ± 033 ± 320 ± 137 ± 146 ± 328 ± 1
UR002 (mntH::kan)19 ± 133 ± 421 ± 234 ± 352 ± 429 ± 1
UR003 (sit::cam mntH::kan)31 ± 4d35 ± 321 ± 154 ± 6d52 ± 327 ± 2
  • a The data presented are the means ± standard errors of the means for three experiments.

  • b 10 μl of 1 M H2O2.

  • c 10 μl of 0.1 M phenazine methosulfate (PMS) or menadione (MD).

  • d Significantly different (P < 0.05) compared to the value for the wild type.