TABLE 1.

Specific T-cell peptides identified using an epitope mapping approach

StrainAntigenEpitope type% Positive cells (avg ± SD)Amino acid positionAmino acid sequence (reference[s])
BALB/c (H-2d)Ag85A/BCD83.96 ± 1.4670-78MPVGGQSSF (9, 13, 28)
Ag85ACD80.92 ± 0.47144-152VYAGAMSGL (9)
Ag85BCD80.90 ± 0.70141-159IYAGSLSAL (13)
Ag85BCD81.78 ± 0.73151-165ALLDPSQGMGPSLIG (9, 13)
TB10.4CD82.42 ± 0.4120-28GYAGTLQSL (28)
C57BL/6 (H-2b)Ag85A/BCD82.69 ± 1.391-19FSRPGLPVEYLQVPSPSMGa
Ag85ACD40.15241-255QDAYNAGGGHNGVFD (13, 41, 52)
Ag85ACD40.18 ± 0.07261-279THSWEYWGAQLNAMKPDLQ (13, 41, 52)a
Ag85BCD40.16241-255QDAYNAAGGHNAVFN (13, 41, 52)
Ag85BCD40.16 ± 0.04261-280THSWEYWGAQLNAMKGDLQS (13, 41, 52)a
TB10.4CD84.98 ± 0.844-12IMYNYPAML
TB10.4CD84.13 ± 1.8473-87SSTHEANTMAMMARD
  • a Sequence covered by two positive overlapping 15-mer peptides. Smaller epitopes are not identified.