Table 3.

DNA content analysis of Caco-2 cells treated with CDT

Time after addition (h)Additiona%bof Caco-2 cells in cell cycle phase:
G0/G1SG2/M
24Medium41.8 ± 0.636.6 ± 6.321.6 ± 6.2
Vector41.9 ± 0.837.8 ± 6.920.3 ± 7.6
CDT19.6 ± 4.244.3 ± 6.436.1 ± 10.6
48Medium48.0 ± 2.637.8 ± 6.114.2 ± 4.4
Vector43.0 ± 3.443.7 ± 8.013.3 ± 5.0
CDT5.7 ± 2.64.6 ± 5.389.7 ± 7.9
72Medium53.1 ± 2.737.1 ± 1.49.8 ± 1.5
Vector44.3 ± 1.949.4 ± 1.46.3 ± 2.1
CDT0.9 ± 1.26.1 ± 7.193.0 ± 6.1
  • a Additions consisted of either RPMI 1640 (medium), an extract from the vector control strain (vector), or the recombinant CDT extract (CDT).

  • b Values are means ± standard deviations.