Table 2.

Results of prophylactic and therapeutic treatment studies with anti-rTox A

Time of 1st dose (h)aDose (mg) and frequency (no. of days)bNo. of hamstersReduction of mortality (%)
−2440, t.i.d. (12)7100
−2440, t.i.d. (7)7100
−2440, t.i.d. (7)7100
−2440, t.i.d. (7)7100
−2440, t.i.d. (7)7100
−2480, q.d. (4)1060
+340, t.i.d. (4)1250
+480, q.d. (3)956
+16–2480, t.i.d. (2)2045
  • a −, before challenge; +, after challenge.

  • b A regimen of 40 mg t.i.d. for 7 days was used in four independent experiments.