TABLE 3.

Increasing DbpA expression diminishes the ability of B. burgdorferi to persist in the heart and joint tissues during chronic infection of immunocompetent micea

InoculumNo. of cultures positive/total no. of specimens examinedNo. of mice infected/total no. of mice inoculated
HeartJointSkinAll sites
13A/E22/C5/54/55/514/155/5
13A/E22/D5/55/55/515/155/5
13A/dbpA′/A2/51/55/58/155/5
13A/dbpA′/B1/52/55/58/155/5
  • a Groups of five BALB/c mice were inoculated with clone 13A/E22/C, 13A/E22/D, 13A/dbpA′/A, or 13A/dbpA′/B and sacrificed 5 months later. Heart, tibiotarsal joint, and skin specimens were harvested and cultured for spirochetes in BSK-H medium.