Table 3.

Cytokine synthesis induced by bacterial invasion of host cells

Target cellCytokine(s) producedInvading organismReference
Epithelial cellsIL-8Salmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes13
IL-8, MCP-1, GM-CSF, TNF-αSalmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes, enteroinvasive E. coli31
Human umbilical endothelial cellsIL-1β, IL-6S. aureus63
Human fibroblastsIFN-βShigella flexneri, enteroinvasiveE. coli26
MacrophagesIL-1βShigella flexneri64