Table 3.

Cytokine synthesis induced by bacterial invasion of host cells

Target cellCytokine(s) producedInvading organismReference
Epithelial cellsIL-8 Salmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes 13
IL-8, MCP-1, GM-CSF, TNF-α Salmonella dublin, Y. enterocolitica, Shigella dysenteriae, Listeria monocytogenes, enteroinvasive E. coli 31
Human umbilical endothelial cellsIL-1β, IL-6 S. aureus 63
Human fibroblastsIFN-β Shigella flexneri, enteroinvasiveE. coli 26
MacrophagesIL-1β Shigella flexneri 64