Table 1.

Effect of TNF70-80 on BAL cell differentials at 24 h, 48 h, and 7 days postadministrationa

TimeTreat- mentTotal cells (105)% BAL:
MacrophagesPMNLymphocytes
24 hControl21.4 ± 2.096.0 ± 2.02.0 ± 0.62.0 ± 1.1
TNF70-8026.7 ± 8.390.0 ± 6.56.3 ± 3.83.7 ± 0.9
48 hControl19.3 ± 7.297.0 ± 2.01.6 ± 0.41.3 ± 1.9
TNF70-8025.1 ± 6.690.0 ± 2.55.7 ± 2.24.0 ± 2.5
7 daysControl18.0 ± 3.899.0 ± 1.00.4 ± 0.40.7 ± 0.2
TNF70-8019.9 ± 7.998.0 ± 2.02.0 ± 1.30 ± 0
  • a Animals were treated with 10 μg of TNF70-80 or control peptide i.t. Results are means and SEM (n = 5 or 6 per time point).