Table 1.

Composition of normal tears in this studya

Patient no.SexAge (yr)EthnicityConcn of protein (mg/ml)Concn of PLA2(μg/ml)Lysozyme activity (mg/ml)
ECL14C-E. coli
BasalStimulatedBasalStimulatedBasalStimulatedBasalStimulated
1Female34Asian14.610.841.033.848.524.61.561.10
2Male28Asian17.19.247.233.444.019.02.121.54
3Male36Caucasian15.87.936.526.937.216.21.741.49
4Female34Finnish8.35.026.424.515.68.81.100.78
5Female25Finnish12.19.631.119.927.37.51.320.93
6Female33Caucasian12.511.338.025.920.213.51.881.36
Mean ± SE13.4 ± 1.288.97 ± 0.9336.7 ± 2.9927.4 ± 2.1932.1 ± 5.4014.9 ± 2.621.62 ± 0.151.20 ± 0.13
  • a PLA2 concentration was measured by ECL immunoassay and by an enzymatic assay with14C-labeled E. coli as the substrate. Lysozyme activity was measured by a lysoplate assay. The concentrations of protein, PLA2, and lysozyme in basal and onion vapor-stimulated tears were compared by paired t tests.P < 0.05 for protein basal versus stimulated, andP < 0.01 for all other basal versus stimulated comparisons within the same column.