Table 1.

Toxin composition and enzymatic activity

ToxinCompositionEnzymatic activitya
LT E. coliheat-labile enterotoxin (holotoxin)Wild-type LT
Trypsin-cleaved LTHolotoxin with nicked, activated LTA>Wild-type LT
rLT-E112DLT holotoxin with mutated A subunit<2% of wild-type LT (6)
rLTBB subunit of LTNone
CTCholera toxin (holotoxin)Wild-type CT
rCTBB subunit of CTNone
  • ↵a Enzymatic activity is ADP-ribosyltransferase activity.