Table 2.

Immunity of mice to tetanus and salmonellaea

ImmunogenNo. survivors/5 challenged
Tetanus challengeSalmonella challenge
BRD84755
BRD93755
Frg C + alhydrogel50
BRD5090ND
None00
  • a Fifteen weeks after immunization, mice were challenged s.c. with 50 LD50 of tetanus toxin. Animals were monitored for signs of tetanus for 4 days. Two weeks after tetanus challenge, surviving and naive control mice were orally challenged with 8 × 108 CFU of wild-type S. typhimuriumSL1344. Mice were observed for 28 days, and fatalities were recorded. ND, not determined.