Table 4.

Serum vibriocidal titers of vaccineesa

ImmunogennGM titer (range) at indicated day after immunization
0 (preimmunization)2842b70230
DeALPS-CT-11911 (5–32)1,090 (320–6,400)884 (220–6,400)629 (20–3,200)330 (64–1,280)
DeALPS-CT-21915 (5–128)1,645 (640–12,800)1,405 (640–12,800)1,253 (400–6,400)588 (128–3,200)
DeALPS1917 (5–128)29 (5–200)30 (5–200)32 (5–200)33 (8–128)
Cellularc 1815 (5–40)3,981 (3,200–12,800)2,343 (1,600–6,400)1,835 (800–6,400)909 (200–3,200)
  • a V. cholerae O1 strain 075, serotype Inaba, was the target organism.

  • b Blood sample taken and volunteer reinjected with the same vaccine.

  • c Wyeth-Ayerst Laboratories, containing 4 × 109 organisms each of V. cholerae O1 serotypes Inaba and Ogawa.