Table 2.

Comparison of immune responses in stool with those in intestinal lavage after two oral immunizations with ETEC vaccinea

ParameterValue (%) for vaccine antigen
CFA/ICS1/3CS2CS4CTB
Sensitivity8854506294
Positive predictive value937071100100
  • ↵a Intestinal lavage samples and fecal extracts from 19 volunteers collected 9 days after the second dose were assayed for specific IgA per total IgA responses to the respective antigens. The percentage of volunteers responding in both stool and lavage in relation to those responding in lavage (sensitivity) and in stool (positive predictive value) is given for each antigen.