TABLE 2.

Virulence of wild-type and isogenic ofs mutant strains of S. suis serotype 2 in pigletsa

Age of infected pigs (wk)Total no. of infected pigsS. suis strainNo. of pigs/total no. of pigs
MorbidityMortalitySevere clinical symptomsbMaximum body temp (°C)
<4040-40.5>40.5
4-59108/98/98/91/90/98/9c
4-5910Δofs2/120/90/90/95/94/90/9
7-84102/41/42/42/41/41/4
7-8410Δofs2/121/41/41/43/40/41/4
  • a German Landrace piglets from a herd free of sly+ epf+ mrp+ cps2 S. suis strains.

  • b In particular, apathy, persistent anorexia, and/or neural disorder (lameness was not observed in any piglet).

  • c All eight piglets had a fever of >41°C.