TABLE 4.

Reisolation of the challenge strain in pigs inoculated with wild-type and isogenic ofs mutant of S. suis serotype 2

Age of infected pigs (wk)Total no. of infected pigsS. suis strainNo. of pigs in which the S. suis challenge straina was isolated/total no. of pigs
TonsilsbLungcSerosadSpleenCerebrospinal fluidJoint fluide
2-7 dpi20 dpi
4-59106/91/17/95/9f2/9g2/9g0/9
4-5910Δofs2/125/96/93/90/90/90/90/9
7-84101/43/30/40/40/41/40/4
7-8410Δofs2/121/41/30/41/40/40/40/4
  • a Challenge strains were identified through PCR assays (see Materials and Methods).

  • b Either tonsil swabs or organ samples.

  • c One cranial lobe was investigated.

  • d Pleural, peritoneal, or pericardial cavity.

  • e One tarsal puncture was investigated.

  • f Four of the five animals were also positive in the lung.

  • g The challenge strain was detectable in multiple organs from these animals.