porA knockout galE OMV vaccine | MenB strain H44/76 | MenB strain Cu385 | MenB strain NZ124/98 | ||||||
---|---|---|---|---|---|---|---|---|---|

Geometric mean titer for 50% killing^{a} | 95% Confidence interval | Seroconversion (%)^{b} | Geometric mean titer for 50% killing | 95% Confidence interval | Seroconversion (%)^{b} | Geometric mean titer for 50% killing | 95% Confidence interval | Seroconversion (%)^{b} | |

No upregulation | 71 | 46-109 | 15 | 59 | 42-82 | 5 | 50 | 50-50 | 0 |

TbpA upregulated | 134 | 61-296 | 30 | 117 | 57-241 | 30 | 85 | 48-149 | 20 |

Hsf upregulated | 74 | 45-122 | 15 | 73 | 44-121 | 15 | 88 | 52-149 | 25 |

TbpA and Hsf upregulated | 727 | 342-1,546 | 90 | 244 | 117-511 | 65 | 222 | 91-542 | 45 |