TABLE 2.

Flow cytometry analysis of cell marker expression of total cell counts from livers of mice inoculated with F. tularensis LVS 5 days earlier compared to that from uninfected livers

Cell markerMean % ± SDa
Uninfected total cellsTotal cells at 5 DPI
CD3+7.6 ± 2.96.1 ± 1.4
B220+3.4 ± 1.33.1 ± 1.7
CD11c+1.1 ± 0.62.8 ± 1.8
CD11c+ Mac-1+0.3 ± 0.32.1 ± 1.6
DX5+ NK1.1+2.3 ± 0.64.8 ± 0.9b
Mac-1+2.3 ± 0.321.3 ± 3.1c
F4/80+ Mac-1+1.8 ± 1.32.8 ± 0.8
MHC-II+ Mac-1+ CD11c1.2 ± 0.210.4 ± 5.2d
Gr-1+ Mac-1+1.5 ± 0.313.1 ± 5.3e
  • a Results are the means ± standard deviations for three mice.

  • b P = 0.015.

  • c P = 0.0005.

  • d P = 0.039.

  • e P = 0.020.