Table 2.

Characteristics of S. flexneri mutants

StrainGenotype% InvasionaPlaque formationb
SA511Parental strain92.0 ± 4.1+
SA2122 vpsC::TnphoA 88.2 ± 2.5P
SA5122 vpsC::TnphoA 83.0 ± 5.6P
SA4100 vpsA::aphA-3 79.3 ± 3.8P
SA2054 ispA::TnphoA 63.3 ± 18.9
  • a Percentage of Henle cells infected with 3 or more bacteria. At least 300 cells were observed per experiment, and means ± standard deviations of three experiments are shown.

  • b +, 1.5- to 2.0-mm-diameter plaques; P, pinpoint (<0.2-mm-diameter) plaques; −, no plaques.