Table 4.

Concentrations of IL-12 p40 subunit in supernatants of colon fragment cultures of IL-10-deficient mice wild-type mice, and heterozygous mice kept in either SPF or germfree conditions

Mouse groupNo. of mice examinedMean IL-12 p40 concentration (pg/ml)a
SPF wild type23<1
SPF IL-10 deficient251,037 ± 105*
Germfree heterozygote10<1
Germfree IL-10 deficient21<1
  • a *, significantly different from all other groups (P < 0.05); for statistical comparison, all other groups were assigned a mean value of 1.