Table 1.

Salmonella and E. coli constructs used for development of K99 fimbria vaccines

Bacterial strainParent strainAttenuationPlasmidK99 fimbriaeReference
S. typhimurium
 SL 7207SL 1344 ΔaroA NoneNone48
 H683SL 7207 ΔaroA Δasd NoneNone17, 48
 H647H683 ΔaroA Δasd pJRD184-asd + None48, this study
 AP112H683 ΔaroA Δasd pMAK99-asd + PresentThis study
E. coli
 H681χ6212 Δasd NoneNone17, 48
 AP111H681 Δasd pMAK99-asd + PresentThis study
 NADC 2323C600 thr leu-6 thi-1 supE44 lacY1 tonA21 pFK99Present9