TABLE 1.

Hemorrhage at necropsy in C57BL/10 mice without or with IL-10 deficiency during acute RF borreliosis

MiceInoculumNo. of mice with hemorrhage in organ/total no. of mice examineda
BrainKidneyLiverLung
WTPBS0/40/40/40/4
B. turicatae serotype 20/80/80/80/8
IL-10−/−PBS0/40/40/40/4
B. turicatae serotype 23/85/85/83/8
  • a Hemorrhages were studied macroscopically at necropsy 4 or 5 days after intraperitoneal inoculation of 5 × 104 B. turicatae spirochetes or PBS as a control.