TABLE 1.

Mortality of BALB/c mice challenged with ETEC strains H10407 and B7Aa

Strain and no. of organismsNo. of dead mice at day postchallenge:Totalb
1234567
H10407
    0c00000000/12 (0)
    1 × 10800000000/12 (0)
    5 × 10803121007/12 (58)
    1 × 10908412/12 (100)
    5 × 109066/6 (100)
B7A
    0c00000000/12 (0)
    1 × 10800000000/12 (0)
    5 × 10800210003/12 (25)
    1 × 109005400110/12 (83)
    5 × 1090156/6 (100)
  • a Mice were challenged i.n. with the bacterial dose in 50 μl of PBS diluent administered dropwise to the external nares of each mouse. The data recorded are a combination of two independent trials, except for the 5 × 109 bacterial dose.

  • b Number of dead mice/total number of mice (percent mortality).

  • c Control mice were administered 50 μl of PBS i.n.