TABLE 1.

Details of the study population

GroupaNo. of individualsAge range (yr)Clinical finding(s)bThorax X-ray resultAdmission EKG finding(s)cClinical classification (NYHA)IITd
IND4122-68AsymptomaticNormalNormalR
CARD I1323-70AsymptomaticNormalLV-QRS, NST-TWC, LAFBIR
CARD II3526-67Asymptomatic, A, DNormalLV-QRS, IIB, VPB, RBBBI-IIR
CARD III2226-65Asymptomatic, D, A, P, O, S, S3, S4, ICAEnlargementLAFB, VPB, RBBB, TAVB, PM, AVBM2I-VR
NI2025-60AsymptomaticNormalNormalNR
  • a The patients were grouped as follows: IND patients had no clinical findings with normal EKG and Thorax X ray, CARD patients had different degrees of heart damage, and NI nonchagasic individuals had negative anti-EPI antibodies.

  • b The main clinical findings were arrhythmia (A), dyspnea (D), palpitations (P), ortopnea (O), syncope (S), third sound (S3), fourth sound (S4), and increased cardiac area (ICA).

  • c EKG findings were low voltage of QRS (LV-QRS), nonspecific ST-T wave changes (NST-TWC), left anterior fascicular block (LAFB), incomplete intraventricular block (IIB), ventricular premature beats (VPB), total AV block (TAVB), pacemaker rhythm (PM), and AV block motif type II (AVBM2).

  • d The anti-EPI indirect immunofluorescence titer (IIT) is a Chagas’ disease routine diagnostic test used to evaluate the titer of anti-EPI antibodies. R, reactive (1:640); NR, nonreactive.