TABLE 2.

Colon weights and crypt heights during C. rodentium infection of the mice in this studya

StrainMean colon wt (mg) at day:Mean crypt ht (μm) at day:
046046
NIH Swiss102 ± 10113 ± 8140 ± 12127 ± 13153 ± 19170 ± 23
C57BL/699 ± 4109 ± 7123 ± 6123 ± 10147 ± 15145 ± 12
BALB/c96 ± 7115 ± 7121 ± 10138 ± 15140 ± 12137 ± 16
129S1/SvImJ100 ± 5115 ± 12136 ± 9125 ± 8145 ± 12157 ± 19
C3H/HeJ105 ± 7143 ± 9b223 ± 17b134 ± 12210 ± 27b265 ± 22b
  • a C. rodentium infection resulted in a time-dependent increase in both colon weights and crypt heights in all three mouse strains studied, but the increases were more rapid in the C3H/HeJ strain. Values are the mean colon weight or crypt height ± 1 SEM from three independent experiments, each with groups of four to five mice.

  • b Significantly higher value than those for all other mouse strains at the same time point (P < 0.05).