TABLE 3.

Numbers of mice per group (n = 5) that developed necrosis by days 7 and 14

Infective doseaNo. of mice that developed necrosis after infection with:
Day post- infectionWild-type M5 GASsloΔ1 mutantsagBΔ1 mutantsloΔ1 sagBΔ1 mutant
∼3 × 10774554
145555
∼3 × 10673530
145531
∼3 × 10571000
141200
  • a At higher infective doses, all mice developed necrosis by day 7.