TABLE 4.

Groups of L. pneumophila lcm/Dot proteins classified according to homology

GroupLevel of homol- ogy between L. pneumophila and C. burnetiiaHomolog on the R64 plasmidIcm/Dot protein(s)
1High+IcmT, IcmP, IcmO, IcmL, IcmK, IcmE, IcmJ, IcmB, DotB, DotC, DotD
2HighIcmS, IcmW
3Low+IcmG, IcmC, IcmD, IcmM, DotA, IcmV, IcmX
4LowIcmQ, IcmN, IcmF, IcmH
5NoIcmR
  • a Proteins classified as having high levels of homology are more than 36% identical and 48% similar. Proteins classified as having low levels of homology are from 19% identical and 27% similar to 35% identical and 47% similar.