TABLE 3.

IgG binding to meningococcal outer membrane proteins in pre- and postvaccination serum samples from 40 vaccinees determined by digital scanning of immunoblots

ProteinMedian IgG binding (range), arbitrary unitsPaIncrease (fold)Responseb (% of vaccinees)
PrevaccinationPostvaccination
P1.7,16 PorA236 (0-1,236)2,276 (400-10,394)0.0019.675
P1.19,15 PorA109 (0-1,087)234 (0-2,556)0.0012.125
P15 PorB182 (0-1,836)5,571 (584-14,001)0.00130.690
Opc50 (0-1,406)1,570 (120-6,643)0.00131.475
Opa5.550 (0-953)589 (0-5,002)0.00111.860
  • a See Table 2 footnote a.

  • b Percentage of vaccinees with a fourfold or greater increase in IgG binding after vaccination.